Existence of antigens cross-linking to tumor associated antigens of enzootic bovine leukosis in normal tissues of the bovine fetus.
نویسندگان
چکیده
منابع مشابه
Enzootic Bovine Leukosis
Bovine Leukemia Virus (BLV) is the etiologic agent of Enzootic Bovine Leukosis, a retrovirus exogenous to the bovine species. Once infected, there is no detectable viraemia but instead there is a strong and persistent immunological response to BLV structural proteins, essentially the gp51 envelope glycoprotein and the mayor core protein p24. We describe the test procedure of an indirect ELISA (...
متن کاملEnzootic Bovine Leukosis
Both EBL and SBL occur in southern Africa and in the Southern African context it will therefore be very important to accurately differentiate between EBL and SBL. The epidemiology, direct and indirect economic impact, diagnosis and most importantly control and eradication of EBL is markedly different to that of SBL. Globally EBL infection may also place severe restrictions on the import and exp...
متن کاملBovine leukaemia virus and enzootic bovine leukosis.
Infection of bovines with bovine leukaemia virus (BLV) manifests itself in either of two ways: 30-70% of carriers develop persistent lymphocytosis (PL), with the viral genome integrated at a large number of different sites in the DNA of the affected B-lymphocytes, without causing any chromosomal abnormalities. Only 0,1-10% of carriers develop lymphoid tumours, which also consist of B-lymphocyte...
متن کاملDetection and Identification of Enzootic Bovine Leukosis (EBL) in Calves in Iran
Enzootic bovine leukosis (EBL) is known as bovine lymphosarcoma and normally affects the old cattle. EBL is caused by bovine leukemia virus (BLV), which is generally spread all around the world. This virus is transmitted via bovine blood products within and between cattle herds. Glycoprotein GP51 in the blood is responsible for cattle immune responses to BLV. This virus has been previously dete...
متن کاملTopographical analysis of tumor-associated antigens on bovine leukemia virus-induced bovine lymphosarcoma.
Tumor-associated antigens (TAAs) expressed on tumor cells from cattle with enzootic bovine leukosis were divided into three groups by using 13 monoclonal antibodies: common TAA; partially common TAA; and individually distinct TAA. TAA was extracted from tumor cells and purified by ion exchange chromatography on diethylaminoethyl-cellulose and isoelectric focusing. The common TAA, which was dete...
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ژورنال
عنوان ژورنال: The Japanese Journal of Veterinary Science
سال: 1987
ISSN: 0021-5295,1881-1442
DOI: 10.1292/jvms1939.49.373